Sermorelin acetate (sermorelin) is the acetate salt of an amidated synthetic 29- amino acid peptide (GRF 1-29 NH 2 ) that corresponds to the amino-terminal segment of the naturally occurring human growth hormone-releasing hormone (GHRH or GRF) consisting of 44 amino acid residues. Acetate Content(by HPLC) :≤15.0%. The structural formula for sermorelin acetate is:
The free base of sermorelin has the empirical formula C 149 H 246 N 44 O 42 S and a molecular weight of 3,358 daltons. Specific Optical Rotation(c=0.5,1%HAc) :-80.0~-90.0°; ater Content(Karl Fischer) :≤6.0%. Molecular Formula: C149H246N44O42.
Sermorelin is a sterile, non-pyrogenic, lyophilized powder intended for subcutaneous injection after reconstitution with Sodium Chloride Injection, USP. The reconstituted solution has a pH of 5.0 to 5.5. For example, "square wave" or pharmacological presentation of the exogenous hormone cannot be avoided since it is administered as a bolus, subcutaneous injection. Appearance :White powder. [CAS No.]: 86168-78-7.
Amino Acid Composition :±10% of theoretical
Purity(by HPLC) :≥98.0%
Single Impurity(by HPLC) :≤1.0%
Peptide Content(by %N ) :≥80%
Assay(By Anhydrous, Acetic Acid-free ) :95.0~105.0%
Bacterial Endotoxins :≤5EU/mg
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