Exenatide Acetate is a white powder which is chemicaly expressed as C187H282N50O60S.
Application of exenatide causes an increase in acinar cAMP without stimulating amylase release. MW is 4186.6. As an incretin mimetic, exenatide acts as agonist of the glucagon-like peptide-1 (GLP-1) receptor. As GLP-1, though with prolonged activity, exenatide augments the postprandial production of insulin and suppresses secretion of glucagon. For this reason, exenatide has found use as a medication of diabetes II.
Exenatide Acetate is used as a 39-amino acid peptide originally isolated from the salivary glands of the Gila monster (Heloderma suspectum), differs from exendin-3 only in two positions close to the N-terminus.
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