Thursday, April 19, 2012

What is Exenatide Acetate?

Exenatide Acetate, a 39-amino acerbic peptide originally abandoned from the salivary glands of the Gila monster (Heloderma suspectum), differs from exendin-3 alone in two positions abutting to the N-terminus. Application of exenatide causes an access in acinar cAMP after aesthetic amylase release. As an incretin mimetic, exenatide acts as agonist of the glucagon-like peptide-1 (GLP-1) receptor. As GLP-1, admitting with abiding activity, exenatide augments the postprandial assembly of insulin and suppresses beard of glucagon. For this reason, exenatide has begin use as a medication of diabetes II.
This artefact is offered and awash alone for uses analytic accompanying to the development and acquiescence of advice beneath a Federal law which regulates the manufacture, use or auction of drugs (the “Bolar Exemption”). Bachem cannot be fabricated accountable for any contravention of bookish acreage rights. It is the sole and alone albatross of the client or user of this artefact to accede with the accordant civic rules and regulations.
Exenatide (INN, marketed as Byetta, Bydureon) is a medication approved in April 2005 for the treatment of diabetes mellitus type 2. It belongs to the group of incretin mimetics and is manufactured by Amylin Pharmaceuticals Exenatide in its Byetta form is administered as a subcutaneous injection (under the skin) of the abdomen, thigh, or arm, any time within the 60 minutes before the first and last meal of the day. A once-weekly injection has been approved as of January 27th, 2012 under the trademark, Bydureon.
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