CRF (human, rat) Acetate stimulates adrenocorticotropic hormone (ACTH)secretory cells in adenohypohhysis to make it secrete ACTH.
It inhibits food intake in mammals. CRF plays a potent role in decreasing food intake in avian species. the efficacy of CRF, urocortin and urotensin I was directly compared using one dose, 0.1 µg. The results indicated that the suppressive effect on food intake was strongest for CRF followed by urotensin I, then urocortin. These results suggest that the structure of receptors for the CRF family in chicks may be somewhat different than in mammals.
Appearance: white powder
Usage: Used for the treatment of adrenal insufficiency and for the emergency treatment of shock.
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