Sequence: p-Glu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2,
supplied as acetate salt
Appearance
White to off-white powder
Solubility
Soluble in water at a concentration of 10 mg/mL to give a clear solution not more intensely colored than reference solution Y5
Gonadorelin acetate for injection is used for the induction of ovulation in women with primary hypothalamic amenorrhea. Gonadorelin acetate is a synthetic decapeptide that is identical in amino acid sequence to endogenous gonadotropin-releasing hormone (GnRH) synthesized in the human hypothalamus and in various neurons terminating in the hypothalamus.
Gonadorelin Acetate injection is contraindicated in women with any condition that could be exacerbated by pregnancy. For example, pituitary prolactinoma should be considered one such condition. Additionally, any history of sensitivity to gonadorelin acetate, gonadorelin hydrochloride or any component of gonadorelin acetate injection is a contraindication.
Gonadorelin acetate injection is intended to initiate events including the production of reproductive hormones (e.g., estrogens and progestins). Therefore, any condition that may be worsened by reproductive hormones, such as a hormonally-dependent tumor, is a contraindication to the use of gonadorelin acetate injection.
More about: Gonadorelin Acetate sale
Read more: Peptides
No comments:
Post a Comment