What is GRF（human）Acetate?

GRF（human）Acetate
Sequence Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly-Ala-Arg-Ala-Arg-Leu-NH2
CAS No. 83930-13-6
Molecular formula C215H358N72O66S
Molecular weight 5039.76
Purity (HPLC) 98.0%min.
Appearance White powder
Peptide content (N%) 80.0%
Growth hormone releasing factor (GRF, somatorelin) is a hypothalamic hormone which regulates the synthesis and secretion of growth hormone from the anterior pituitary.
Growth-hormone-releasing hormone (GHRH), aswell accepted as growth-hormone-releasing agency (GRF, GHRF), somatoliberin or somatocrinin, is a absolution hormone for advance hormone. It is a 44-amino acerbic peptide hormone produced in the arcuate basis of the hypothalamus.
GHRH aboriginal appears in the animal hypothalamus amid 18 and 29 weeks of gestation, which corresponds to the alpha of assembly of advance hormone and added somatotropes in fetuses.
GHRH is appear from neurosecretory assumption terminals of these arcuate neurons, and is agitated by the hypothalamo-hypophyseal aperture arrangement to the antecedent pituitary gland area it stimulates advance hormone (GH) beard by aesthetic the advance hormone-releasing hormone receptor. GHRH is appear in a pulsatile manner, aesthetic agnate pulsatile absolution of GH. In addition, GHRH aswell promotes slow-wave beddy-bye directly. Advance hormone is appropriate for accustomed postnatal growth, cartilage growth, authoritative furnishings on protein, carbohydrate, and lipid metabolism.
GHRH stimulates GH assembly and absolution by bounden to the GHRH Receptor (GHRHR) on beef in the antecedent pituitary. The GHRHR is a affiliate of the secretin ancestors of G protein-coupled receptors, and is amid on chromosome 7. This protein is transmembranous with seven folds, and its atomic weight is about 44 kD. GHRH bounden to GHRHR after-effects in added GH assembly mainly by the cAMP abased pathway, but aswell by the phospholipase C alleyway (IP3/DAG pathway), and added accessory pathways.
The accomplishments of GHRH are against by somatostatin (growth-hormone-inhibiting hormone). Somatostatin is appear from neurosecretory assumption terminals of periventricular somatostatin neurons, and is agitated by the hypothalamo-hypophysial aperture apportionment to the antecedent pituitary area it inhibits GH secretion. Somatostatin and GHRH are buried in alternation, giving acceleration to the clearly pulsatile beard of GH.
GHRH announcement has been approved in borderline beef and tissues alfresco its capital website in the hypothalamus, for example, in the pancreas, epithelial film of the gastrointestinal amplitude and, pathologically, in tumour cells.
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What is Atriopeptin II?

Sequence
Ser-Ser-Cys-Phe-Gly-Gly-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg
Biochem/physiol Actions
Activates particulate guanylyl cyclase, cardiac atrial peptide which relaxes both intestinal and vascular smooth muscle.
Atrial natriuretic peptide (ANP), atrial natriuretic agency (ANF), atrial natriuretic hormone (ANH), or atriopeptin, is a able vasodilator, and a protein (polypeptide) hormone buried by affection beef cells. It is complex in the homeostatic ascendancy of physique water, sodium, potassium and fat (adipose tissue). It is appear by beef beef in the top accommodation (atria) of the affection (atrial myocytes) in acknowledgment to top claret pressure. ANP acts to abate the water, sodium and adipose endless on the circulatory system, thereby abbreviation claret pressure.
Atriopeptin is a 28-amino acerbic peptide with a 17-amino acerbic ring in the average of the molecule. The ring is formed by a disulfide band amid two cysteine residues at positions 7 and 23. ANP is carefully accompanying to BNP (brain natriuretic peptide) and CNP (C-type natriuretic peptide), which all allotment the aforementioned amino acerbic ring. ANP was apparent in 1981 by a aggregation in Kingston, Ontario, Canada afterwards they fabricated the seminal ascertainment that bang of atrial (but not ventricular) tissue extracts into rats acquired copious natriuresis.
Physiological effects
ANP binds to a specific set of receptors - ANP receptors. Receptor-agonist bounden causes a abridgement in claret aggregate and accordingly a abridgement in cardiac achievement and systemic claret pressure. Lipolysis is added and renal sodium reabsorption is decreased. The all-embracing aftereffect of ANP on the physique is to adverse increases in claret burden and aggregate acquired by the renin-angiotensin system.
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Precautions of Exenatide Acetate

Exenatide Acetate
Sequence
H-His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2 acetate salt
Exenatide Acetate is white powder.
Exenatide Acetate is used for a treatment of type 2 diabetes and the mechanism is similar to that of GLP-1.
Precautions of Exenatide Acetate
Use carefully in:
astringent renal crime or end-stage renal disease, astute pancreatitis, astringent GI disease
circumstantial use of insulin, thiazolidinediones, D-phenylalanine derivatives, meglitinides, or alpha-glucosidase inhibitors
abundant or breastfeeding patients
accouchement (safety and ability not established).
Exenatide, a 39-amino acerbic peptide originally abandoned from the salivary glands of the Gila monster (Heloderma suspectum), differs from exendin-3 alone in two positions abutting to the N-terminus. Application of exenatide causes an access in acinar cAMP after aesthetic amylase release. As an incretin mimetic, exenatide acts as agonist of the glucagon-like peptide-1 (GLP-1) receptor. As GLP-1, admitting with abiding activity, exenatide augments the postprandial assembly of insulin and suppresses beard of glucagon. For this reason, exenatide has begin use as a medication of diabetes II.
Exenatide Acetate is offered and awash alone for uses analytic accompanying to the development and acquiescence of advice beneath a Federal law which regulates the manufacture, use or auction of drugs (the “Bolar Exemption”). Bachem cannot be fabricated accountable for any contravention of bookish acreage rights. It is the sole and alone albatross of the client or user of this artefact to accede with the accordant civic rules and regulations.
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Specifications of g-Endorphin

g-Endorphin
CAS No.:61512-77-4
Molecular Formula:C83H131N19O27S1
Formula Weight:1859.1
Format
Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Precautions
g-Endorphin is for research use only. Not for use in diagnostic or therapeutic procedures.
Endorphins ("endogenous morphine") are endogenous opioid peptides that function as neurotransmitters. They are produced by the pituitary gland and the hypothalamus in vertebrates during exercise, excitement, pain, consumption of spicy food, love and orgasm, and they resemble the opiates in their abilities to produce analgesia and a feeling of well-being.
The term implies a pharmacological activity (analogous to the activity of the corticosteroid category of biochemicals) as opposed to a specific chemical formulation. It consists of two parts: endo- and -orphin; these are short forms of the words endogenous and morphine, intended to mean "a morphine-like substance originating from within the body."
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What is Cetrorelix Acetate used for?

Cetrorelix Acetate (Set-roh-ree-lix ass-it-ate) is a medicine which is used in female infertility and male infertility.
Cetrorelix acetate for injection is a synthetic decapeptide with gonadotropin- releasing hormone (GnRH) antagonistic activity. Cetrorelix acetate is an analog of native GnRH with substitutions of amino acids at positions 1, 2, 3, 6, and 10. The molecular formula is Acetyl-D-3-(2´-naphtyl)-alanine-D-4-chlorophenylalanine-D-3-(3´-pyridyl)- alanine-L-serine-L-tyrosine-D-citruline-L-leucine-L-arginine-L-proline-D-alanine-amide, and the molecular weight is 1431.06, calculated as the anhydrous free base.
Cetrorelix Acetate 0.25 mg or 3 mg is a sterile lyophilized powder intended for subcutaneous injection after reconstitution with Sterile Water for Injection, USP (pH 5-8), that comes supplied in either a 1.0 mL (for 0.25 mg vial) or 3.0 mL (for 3 mg vial) pre-filled syringe. Each vial of Cetrotide® (cetrorelix) 0.25 mg (multiple dose regimen) contains 0.26-0.27 mg cetrorelix acetate, equivalent to 0.25 mg cetrorelix, and 54.80 mg mannitol. Each vial of Cetrotide (cetrorelix)  3 mg (single dose regimen) contains 3.12-3.24 mg cetrorelix acetate, equivalent to 3 mg cetrorelix, and 164.40 mg mannitol.
Cetrorelix acetate prevents the production of certain types of hormones in the body. It is used to treat infertility.
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What is VSV-G Peptide?

Description of VSV-G Peptide
A vesicular stomatitis virus G (VSV-G) protein fragment.
Sequence
(Three-Letter Code)H - Tyr - Thr - Asp - Ile - Glu - Met - Asn - Arg - Leu - Gly - Lys - OH
Format
Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Precautions
VSV-G Peptide is for research use only. Not for use in diagnostic or therapeutic procedures.
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Application of DTrp-Gamma MSH

DTrp-Gamma MSH
Sequence Tyr-Val-Met-Gly-His-Phe-Arg-DTrp-Asp-Arg-Phe-Gly
Molecular Formula: C74H99N21O16S1
Formula Weight:1570.81
Application of DTrp-Gamma MSH
It is a Melanocyte Stimulating Hormones (MSH),which can stimulate the production and release of melanin (melanogenesis) by melanocytes in skin and hair. MSH released into the brain has effects on appetite and sexual arousal.
Format
Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Precautions
This product is for research use only. Not for use in diagnostic or therapeutic procedures.
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Where to find (Ser140)-Myelin Proteolipid Protein (139-151) (depalmitoylated), human, bovine, dog, mouse, rat?

(Ser140)-Myelin Proteolipid Protein (139-151) (depalmitoylated), human, bovine, dog, mouse, rat
Formula: C72H104N20O17
M.W.: 1521.70
Sequence: His-Ser-Leu-Gly-Lys-Trp-Leu-Gly-His-Pro-Asp-Lys-Phe
Myelin proteolipid protein is the major myelin protein from the central nervous system (CNS). It plays an important role in the formation or maintenance of the multilamellar structure of myelin. Myelin proteolipid protein is a highly conserved hydrophobic protein of 276 to 280 amino acids which seems to contain four transmembrane segments, two disulphide bonds and which covalently binds lipids (at least six palmitate groups in mammals). PLP is highly related to M6, a neuronal membran glycoprotein.
Format
Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Precautions
(Ser140)-Myelin Proteolipid Protein (139-151) (depalmitoylated), human, bovine, dog, mouse, rat is for research use only. Not for use in diagnostic or therapeutic procedures.
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How to get b-Endorphin, rat?

Endorphins ("endogenous morphine") are endogenous opioid peptides that function as neurotransmitters. They are produced by the pituitary gland and the hypothalamus in vertebrates during exercise, excitement, pain, consumption of spicy food, love and orgasm,and they resemble the opiates in their abilities to produce analgesia and a feeling of well-being.
β-Endorphin is released into blood from the pituitary gland and into the spinal cord and brain from hypothalamic neurons. The β-endorphin that is released into the blood cannot enter the brain in large quantities because of the blood-brain barrier, so the physiological importance of the β-endorphin that can be measured in the blood is far from clear. β-Endorphin is a cleavage product of pro-opiomelanocortin (POMC), which is also the precursor hormone for adrenocorticotrophic hormone (ACTH). The behavioural effects of β-endorphin are exerted by its actions in the brain and spinal cord, and it is presumed that the hypothalamic neurons are the major source of β-endorphin at these sites. In situations where the level of ACTH is increased (e.g., Cushing’s Syndrome), the level of endorphins also increases slightly.
β-Endorphin has the highest affinity for the μ1 opioid receptor, slightly lower affinity for the μ2 and δ opioid receptors, and low affinity for the κ1 opioid receptors. μ-Opioid receptors are the main receptor through which morphine acts. In the classical sense, μ opioid receptors are presynaptic, and inhibit neurotransmitter release; through this mechanism, they inhibit the release of the inhibitory neurotransmitter GABA, and disinhibit the dopamine pathways, causing more dopamine to be released. By hijacking this process, exogenous opioids cause inappropriate dopamine release, and lead to aberrant synaptic plasticity, which causes dependency. Opioid receptors have many other and more important roles in the brain and periphery however, modulating pain, cardiac, gastric and vascular function as well as possibly panic and satiation, and receptors are often found at postsynaptic locations as well as presynaptically.
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What is Histrelin Acetate?

Histrelin Acetate is a nonapeptide analog of gonadotropin-releasing hormone (GnRH) with added potency. When present in the bloodstream, it acts on accurate beef of the pituitary gland alleged gonadotropes. Histrelin stimulates these beef to absolution luteinizing hormone and follicle-stimulating hormone. Thus it is advised a gonadotropin-releasing hormone agonist or GnRH agonist.
Histrelin is marketed by Endo Pharmaceuticals beneath the cast names Vantas and Supprelin LA.
Histrelin is a man-made version of a hormone that is similar to the one normally released from the hypothalamus gland in the brain. It works in the brain to reduce the blood levels of sex hormones, such as testosterone and estrogen. The histrelin implant is placed under the skin. The implant releases small amounts of histrelin in the body every day for 12 months.
Histrelin is used to treat advanced prostate cancer in adults. It will reduce the level of testosterone, a male hormone, in the blood. Testosterone makes most prostate cancers grow. Histrelin is not a cure for prostate cancer, but it may help relieve the symptoms.
Histrelin Acetate is a potent LHRH (GnRH) agonist. After a transient increase, continuous administration of histrelin results in downregulation of LH and FSH levels followed by a suppression of ovarian and testicular steroid biosynthesis.
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Where to get R-G-D-V?

R-G-D-V inhibited the release of granular proteins from platelets associated with thrombus (platelet factor 4, beta-thromboglobulin; P less than 0.01), but did not prevent the appearance of fibrinopeptide A in circulating blood (P greater than 0.1). No systemic alterations in blood pressure, bleeding time, or platelet aggregation ex vivo were produced by locally infused RGDV. The antithrombotic effects of RGDV peptide disappeared within 5 min after discontinuing the infusion. In control studies infused RGEV (Arg-Gly-Glu-Val, 100 microM) showed no antithrombotic activity. Thus, RGDV selectively blocks platelet-dependent thrombus formation in vivo.
Sequence: {ARG} {GLY} {ASP} {VAL}
Formula: C17H31N7O7
R-G-D-V is a member of Phytoreovirus. It was determined that R-G-D-V is the nucleotide sequence of genome segment S11 of rice gall dwarf virus. The segment RGDV encodes a putative protein of 40 kDa that exhibits approximately 37% homology at the amino acid level to the nonstructural proteins Pns10 of rice dwarf and wound tumor viruses. which are other members of Phytoreovirus.
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What is Herpes Virus Inhibitor 2?

Herpoxin, herpes virus inhibitor consists of two proteins isolated from snake venom of Naja n. kaouthia, which separately and together inhibit the replication of herpes simplex viruses type 1 and type 2 in cell cultures. Herpoxin is characterized as a purified component of snake venom, of the phospholipase A2 (PhA2) enzyme family, which inhibits production of the typical cytopathogenic effects (CPE) produced by herpes viruses type 1 and type 2. Herpoxin consists of two peptides Herp-A and Herp-B having molecular weights 14,000 and 15,000 daltons, respectively, as revealed by gel electrophoresis. The partial sequence for the first fifteen N-terminal amino acids of both Herp-A and Herp-B is: Asn-Leu-Tyr-Gln-Phe-Lys-Asn-Met-Ile-Gln-Cys-Thr-Val-Pro-Asn, which will be referred to as SEQ ID No: 1. The known partial sequences for Herp-A and Herp-B proteins are identical and are typical of phospholipases. However, Herp-A and Herp-B are antigenicaily distinct. Herpoxin is claimed for its method of purification and as a treatment for herpes virus type 1 and type 2 induced oral and genital lesions and other infections. Herpoxin is further claimed as a therapeutic agent for non invasive topical application to treat other viral infections such as: herpes zoster, Kaposi sarcoma in AIDS patents, eczema, etc. It is also an object of this invention to provide Herpoxin as a composition for the treatment of skin infections induced by other microbial agents.
Herpes simplex is a viral disease caused by both Herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2). Infection with the herpes virus is categorized into one of several distinct disorders based on the site of infection. Oral herpes, the visible symptoms of which are colloquially called cold sores or fever blisters, is an infection of the face or mouth. Oral herpes is the most common form of infection. Genital herpes, known simply as herpes, is the second most common form of herpes. Other disorders such as herpetic whitlow, herpes gladiatorum, ocular herpes (keratitis), cerebral herpes infection encephalitis, Mollaret's meningitis, neonatal herpes, and possibly Bell's palsy are all caused by herpes simplex viruses.
Herpes viruses cycle between periods of active disease—presenting as blisters containing infectious virus particles—that last 2–21 days, followed by a remission period. Genital herpes, however, is often asymptomatic, though viral shedding may still occur. After initial infection, the viruses are transported along sensory nerves to the sensory nerve cell bodies, where they become latent and reside life-long. Causes of recurrence are uncertain, though some potential triggers have been identified, including immunosuppressant drugs. The previously latent virus then multiplies new virus particles in the nerve cell and these are transported along the axon of each neuron to the nerve terminals in the skin, where they are released. Over time, episodes of active disease reduce in frequency and severity.
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Where to get CJC-1295?

CJC-1295 is a tetrasubstituted 30-amino acid peptide hormone, primarily functioning as a growth hormone releasing hormone (GHRH) analog. It was invented by ConjuChem, a Canadian biotechnology company.
One of the advantages of CJC-1295 over traditional GHRH or rHGH is its ability to bioconjugate with serum albumin, thus increasing its half-life and therapeutic window. It accomplishes this by using protecting groups around the amino acids of GHRH typically susceptible to enzymatic degradation.
ConjuChem initiated clinical trials for  CJC-1295 during the mid-2000s. The objective of the drug was to treat visceral fat deposits in obese AIDS patients, as increased levels of exogenous HGH are presumed to increase lipolysis (fat loss). The trial was ultimately successful for most research subjects, but the drug's marketing stalled when three of the trial's patients suffered a myocardial infarction.
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What is Gonadorelin Acetate?

Gonadorelin Acetate
Sequence: p-Glu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2,
supplied as acetate salt
Appearance    
White to off-white powder
Solubility    
Soluble in water at a concentration of 10 mg/mL to give a clear solution not more intensely colored than reference solution Y5
Gonadorelin acetate for injection is used for the induction of ovulation in women with primary hypothalamic amenorrhea. Gonadorelin acetate is a synthetic decapeptide that is identical in amino acid sequence to endogenous gonadotropin-releasing hormone (GnRH) synthesized in the human hypothalamus and in various neurons terminating in the hypothalamus.
Gonadorelin Acetate injection is contraindicated in women with any condition that could be exacerbated by pregnancy. For example, pituitary prolactinoma should be considered one such condition. Additionally, any history of sensitivity to gonadorelin acetate, gonadorelin hydrochloride or any component of gonadorelin acetate injection is a contraindication.
Gonadorelin acetate injection is intended to initiate events including the production of reproductive hormones (e.g., estrogens and progestins). Therefore, any condition that may be worsened by reproductive hormones, such as a hormonally-dependent tumor, is a contraindication to the use of gonadorelin acetate injection.
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Description of Histatin 5

Histatin 5 is a human basic salivary anti-microbial peptide with strong fungicidal properties.
Histatins are anti-microbial peptides begin in saliva. They are anticipation to be the above forerunner to the careful proteinaceous structures on tooth surfaces.
Function: Histatins are salivary proteins that are considered to be major precursors of the protective proteinaceous structure on tooth surfaces (enamel pellicle). In addition, histatins exhibit antibacterial and antifungal activities. Histatin-3 1/24 (Histatin 5) is especially effective against C.albicans and C.neoformans, and inhibits Lys-gingipain and Arg-gingipain (rgpB) from P.gingivalis. In addition, histatin-3 1/24 is a potent inhibitor of metalloproteinases MMP2 and MMP9.
Histatins are human histidine-rich and mostly cationic proteins identified originally by Oppenheim et al (1988) as antimicrobial and fungistatic peptides in human parotid and submandibular-sublingual gland secretions. Histatins possess antimicrobial activity against a broad spectrum of bacteria and fungi. Some histatins have been found to be binding proteins for tannins Histatin-5 has been shown to be a strong inhibitor of trypsin-like protease produced by Bacteroides gingivalis and also inhibits Clostripain. Gusman et al (2001) have reported that histatin-5 inhibits the activities of MMP-2 and MMP-9. In addition, Histatin is acftive against the human parasitic protozoa Leishmania.
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One kind of Lipotropin-b-Lipotropin (61-64)

Lipotropin is a hormone produced by the break of pro-opiomelanocortin (POMC). The antecedent pituitary gland produces the pro-hormone POMC, which undergoes break to adrenocorticotropin (ACTH) and β-lipotropin (β-LPH).
β-Lipotropin is a 90-amino acid polypeptide that is the carboxy-terminal fragment of POMC.
It stimulates melanocytes to produce melanin, and can also be cleaved into smaller peptides. In humans, γ-lipotropin, α-MSH, β-MSH, γ-MSH, α-endorphin, β-endorphin, γ-endorphin, and met-enkephalin are all possible fragments of β-lipotropin.
β-Lipotropin also performs lipid-mobilizing functions such as lipolysis and steroidogenesis.
γ-lipotropin is the amino-terminal peptide fragment of β-lipotropin. In humans, it has 56 amino acids.
Lipotropin is a polypeptide hormone produced by the pituitary gland. This hormone stimulates fat burning and is present at the release of endorphins. Lipotropin supplements are in a class of growth hormones that may be taken to increase muscle mass and decrease body fat.
Human growth hormones (hGH) are responsible for optimizing the performance of glands and organs. As people age, hGH depletes. Lipotropin stimulates hGH and thus slows the aging process.
Lipotropin is offered in liquid form to be sprayed under the tongue for immediate, effective absorption into the bloodstream. It is usually recommended that the spray be used morning and night. Supplements are also offered in capsule form. Anti-aging properties of lipotropin are said to include fat loss, boosted energy levels, enhanced immune system, and wrinkle reduction.
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Where to get b-Defensin-1, human?

Beta defensins are a family of mammalian defensins. The beta defensins are antimicrobial peptides implicated in the resistance of epithelial surfaces to microbial colonization.
Defensins are 2-6 kDa, cationic, microbicidal peptides active against many Gram-negative and Gram-positive bacteria, fungi, and enveloped viruses, containing three pairs of intramolecular disulfide bonds. On the basis of their size and pattern of disulfide bonding, mammalian defensins are classified into alpha, beta and theta categories. Every mammalian species explored thus far has beta-defensins. In cows, as many as 13 beta-defensins exist in neutrophils. However, in other species, beta-defensins are more often produced by epithelial cells lining various organs (e.g. the epidermis, bronchial tree and genitourinary tract.
b-Defensin-1 is one of a family of small cationic peptides with the ability to disrupt cell membranes, resulting in antimicrobial and possibly anti-tumour activity. The protein is expressed in the distal nephron. The gene, along with those of the other members of the family of defensin, is at 8p23 and is deleted in conventional renal cell carcinoma.
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Precautions of Arg8 a-Neo-Endorphin (1-8) 1

Arg8 a-Neo-Endorphin (1-8) 1
Sequence: Tyr-Gly-Gly-Phe-Leu-Arg-Lys-Arg
Formula: C46H73N15O10
Molecular Weight: 996.2
Format
Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Precautions of Arg8 a-Neo-Endorphin (1-8) 1
This product is for research use only. Not for use in diagnostic or therapeutic procedures.
α-Neoendorphin is an endogenous opioid peptide with a decapeptide structure and the amino acid sequence Tyr-Gly-Gly-Phe-Leu-Arg-Lys-Tyr-Pro-Lys.
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Where to get Histrelin Acetate?

Histrelin Acetate is a nonapeptide analog of gonadotropin-releasing hormone (GnRH) with added potency. When present in the bloodstream, it acts on particular cells of the pituitary gland called gonadotropes. Histrelin stimulates these cells to release luteinizing hormone and follicle-stimulating hormone. Thus it is considered a gonadotropin-releasing hormone agonist or GnRH agonist.
Histrelin is marketed by Endo Pharmaceuticals under the brand names Vantas and Supprelin LA.
Histrelin Acetate is a potent LHRH (GnRH) agonist. After a transient increase, continuous administration of histrelin results in downregulation of LH and FSH levels followed by a suppression of ovarian and testicular steroid biosynthesis.
Indications
Histrelin is used to treat hormone-sensitive cancers of the prostate in men and uterine fibroids in women. In addition, histrelin has been proven to be highly effective in treating central precocious puberty in children.
It is available as a daily intramuscular injection.
Histrelin is also available in a 12-month subcutaneous implant (Vantas) for the palliative treatment of advanced prostate cancer.
A 12-month subcutaneous implant (Supprelin LA) for central precocious puberty (CPP) was approved on May 3, 2007 by the U.S. Food and Drug Administration.
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How to find R-G-D-T？

R-G-D-T is short of Random Gap Detection Test.
The Random Gap Detection Test is a modification of the Auditory Fusion Test-Revised with the following improvements. The auditory gap detection threshold of tones and white noise (clicks) is obtained by having the subject identify when signal pairs are separated in time from 0 to 40 msec. The major improvement in the signal presentation during the RGDT is that the gap interval is randomly assigned, and therefore unpredictable to the subject. The test includes stimuli at four frequencies (500, 1000, 2000, and 4000 Hz) and white noise clicks of 50 microseconds duration. A practice session is presented with tone pairs at 1000 Hz. The test takes approximately 10 minutes to administer, including instructions and practice. Interpretation is made by averaging the gap detection threshold for all tonal stimuli and comparing the results to normative data that is currently available on subjects from 5 to 12 years of age.
Results of R-G-D-T can help identify individuals whose language and reading disorder may be related to a fundamental disorder in temporal processing. These are disorders of auditory timing in which the individual is unable to perceive rapid changes in formant frequencies of ongoing speech. Once these problems are identifies remediation programs to enable the individual to compensate for their problem can be recommended. In addition, this particular disorder may benefit from certain programs designed to remediate these problems at the perceptual level. . .
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Specifications of Endostatin (84-114)-NH2 (JKC367)

Endostatin (84-114)-NH2 (JKC367)
Sequence:
Pro-Gly-Ala-Arg-Ile-Phe-Ser-Phe-Asp-Gly-Lys-Asp-Val-Leu-Arg-His-Pro-Thr-Trp-Pro-Gln-Lys-Ser-Val-Trp-His-Gly-Ser-Asp-Pro-Asn-NH2
Formula: C161H236N48O43
Molecular Weight: 3531.9
Format:
Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Storage: Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Precautions of Endostatin (84-114)-NH2 (JKC367)
Endostatin (84-114)-NH2 (JKC367) is for research use only. Not for use in diagnostic or therapeutic procedures.
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Specifications of Eledoisin Acetate

Eledoisin Acetate
Sequence pGlu-Pro-Ser-Lys-Asp-Ala-Phe-Ile-Gly-Leu-Met-NH2
CAS No. 69-25-0
Molecular formula C54H85N13O15S
Molecular weight 1188.44
Purity (HPLC)99.0%
Appearance White powder
Peptide content (N%) 80%(by %N)
Eledoisin Acetate is an acetate salt form of Eledoisin which is a decapeptide from the posterior salivary gland of a species of snail (Eledone) and a nonselective neurokinin receptor agonist. It has vasodilator, hypotensive and extravascular smooth muscle stimulant properties.  It was first isolated from the posterior salivary glands of two mollusk species Eledone muschata and Eledone aldovandi, which belong to the octopod order of Cephalopoda.
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Descriptions of Cecropin A (1-8)-Melittin (1-18) amide

Sequence of Cecropin A (1-8)-Melittin (1-18) amide   
Lys-Trp-Lys-Leu-Phe-Lys-Lys-Ile-Gly-Ile-Gly-Ala-Val-Leu-Lys-Val-Leu-Thr-Thr-Gly-Leu-Pro-Ala-Leu-Ile-Ser-NH2
Formula: C136H233N33O29
MW :2794.55
Storage: -15 °C
Description of Cecropin A (1-8)-Melittin (1-18) amide
This is a Cecropin A (CA) –melittin (M) hybrid peptide, named CA(1-8)M(1-18)-NH2. It consists of Cecropin A amino acid residues 1-8 and melittin amino acid residues 1-18. Its bactericidal activity in animals raises the potential for this peptide to be a good clinical remedy against the increasing threat of a widespread pan-resistant Acinetobacter baumannii. A shorter version of this hybrid peptide, CA(1-7)M(2-9), cat# 63890, is equally effective in animal study.
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Specifications of Glp6 Substance P (6-11)

Description of Glp6 Substance P (6-11)
Glp6 Substance P (6-11) increased the blood pressure after injection into the cerebral ventricles.
Sequence: Glp-Phe-Phe-Gly-Leu-Met-NH2
Formula: C36H49N7O7S1
Molecular Weight: 723.9
Format
Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Precautions
Glp6 Substance P (6-11) is for research use only. Not for use in diagnostic or therapeutic procedures.
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Format of C-telopeptide

Description of C-telopeptide
Format
Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt.
The C-telopeptide is an octapeptide corresponding to the C-terminus region (aa 1207-1214) of the alpha-1 chain of type 1 collagen. The presence of the C-telopeptide in urine samples is a good marker of osteoclast-mediated bone resorption observed in osteoporosis, Paget's disease, primary hyperparathyroidism, renal insufficiency and bone metastases.
Sequence
H-Glu-Lys-Ala-His-Asp-Gly-Gly-Arg-OH or H-EKAHDGGR-OH
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What is b-Endorphin, camel?

b-Endorphin, camel
Sequence: H-Tyr-Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu-Phe-Lys-Asn-Ala-Ile-Ile-Lys-Asn-Ala-His-Lys-Lys-Gly-Gln-OH;
b-Endorphin, camel is an almighty autogenous opioid protein that is acquired from propiomelanocortin, a protein begin in the brain, antecedent pituitary, skin, allowed system, and added borderline sites. Ib-Endorphin, camel is appear in acknowledgment to aching stimuli and has almighty antinociceptive activity that is advised through its activity on μ receptors in academician and by μ and κ receptors in the analgesic cord.
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What is DAla2 b-Lipotropin (61-69)?

Description of DAla2 b-Lipotropin (61-69)
The constructed peptide was HPLC purified, lyophilized with 100% acetonitrile and is supplied as a powder. The peptide can be reconstituted in band-aid application the adapted absorber as needed.It is advance air-conditioned at 2-8°C for up to 6 months. For continued appellation accumulator abundance at -20°C.This artefact is for analysis use only. Not for use in analytic or ameliorative procedures.DAla2 b-Lipotropin (61-69) is acrid in water. The capacity of this canteen accept been accurately determined. Both the admiration and the canteen accept been siliconized. Do not attack to weight out a abate allocation of the contents.Before using, abundance the peptide in the DRY anatomy at 0 - 5 °C. For best and repeatable results, rehydrate the peptide anon afore using. Do not re-freeze any bare portions.
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Specifications of Argireline Acetate(Acetyl Hexapeptide-3)?

Synonyms
N-Acetyl-L-alpha-glutamyl-L-alpha-glutamyl-L-methionyl-L-glutaminyl-L-arginyl-L-argininamide
Molecular Formula: C34H60N14O12S
Molecular Weight: 888.99
CAS Registry Number: 616204-22-9
SPECIFICATIONS of Argireline Acetate(Acetyl Hexapeptide-3)
1 .Appearance :White powder
2 .Water Content(Karl Fischer) :≤5.0%
3 .Acetate Content(by HPLC) :≤15.0%
4 .Amino Acid Composition :±10% of theoretical
5 .Purity (by HPLC) :≥95.0% 
6 .Single Impurity(by HPLC) :≤2.0% 
7 .Peptide Content(by %N ) :≥80%
8 .Assay(By Anhydrous, Acetic Acid-free ) :95.0~105.0%
9 .Bacterial Endotoxins :≤10EU/mg
Packing: plastic vial(dedicated for peptide packing) or glass vial, quantity according to customer's detail requirement.
Storag: a cool(2~8 °C) & dry place protected from light, keep package close when not in use.
Argireline is the barter name for Acetyl Hexapeptide-3, a constructed anti-aging corrective additive acquired from accustomed proteins. It is a peptide, a alternation fabricated up of amino acids. Argireline has been apparent in assay studies to advice abatement the arresting furnishings of crumbling by allowance abbreviation the abysmal wrinkles and curve that action about the forehead and eyes. As a result, a ample bulk of cosmetics companies cover Argireline in the conception of their anti-aging products.
Argireline Acetate(Acetyl Hexapeptide-3) is an acetate alkali anatomy of argireline which works by destabilizing what is alleged the SNAP receptor circuitous and decreases the arresting signs of crumbling y abbreviation the abysmal wrinkles and curve that action about the forehead and eyes. It is a constructed anti-aging corrective acquired from accustomed proteins. NAP receptor circuitous s all-important for the abbreviating of muscles. In accession to this, it aswell slows or even stops the boundless absolution of catecholamine, which is accepted to advice in contraction formation. Studies appearance that applying a baby bulk (about 5-10%) of the band-aid over a aeon of 20 to 25 canicule can appearance absolute after-effects with bigger derma texture. Derma cartography assay of an oil/water (O/W) chrism absolute 10% of the hexapeptide on advantageous women volunteers bargain contraction abyss up to 30% aloft 30 canicule treatment.
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Where to get Argireline Acetate(Acetyl Hexapeptide-3)?

Argireline Acetate(Acetyl Hexapeptide-3) is an acetate salt form of argireline which works by destabilizing what is called the SNAP receptor complex and decreases the visible signs of aging y reducing the deep wrinkles and lines that occur around the forehead and eyes. It is a synthetic anti-aging cosmetic derived from natural proteins. NAP receptor complex s necessary for the contraction of muscles. In addition to this, it also slows or even stops the excessive release of catecholamine, which is known to help in wrinkle formation. Studies show that applying a small amount (about 5-10%) of the solution over a period of 20 to 25 days can show positive results with improved skin texture. Skin topography analysis of an oil/water (O/W) emulsion containing 10% of the hexapeptide on healthy women volunteers reduced wrinkle depth up to 30% upon 30 days treatment.
Argireline Acetate(Acetyl Hexapeptide-3), Argireline is a peptide attached with an acetyl group. It is formulated to relax facial muscles by disrupting the nerve signals sent to tense muscles below the dermis, reduce the degree of existing wrinkles and stop their future development. It reduces the depth of wrinkles on the face caused by the contraction of muscles from facial expressions, especially around the eyes, mouth, and on the forehead. Argireline is a unique new anti-wrinkle peptide that has been shown to be significantly effective against the development of skin wrinkling, being a safer and milder alternative to Botulinum Toxin. This hexapeptide represents the discovery of a positive hit based on a scientific pathway from rational design to GMP production. The study of the basic biochemical mechanisms of anti-wrinkle activity has LED to this Argireline has been proved to work in vitro".
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Where to find Dermorphin?

Dermorphin is a hepta-peptide first isolated from the skin of South American frogs belonging to the genus Phyllomedusa. The peptide is a natural opioid that binds as an agonist with high potency and selectivity to mu Opioid receptors. Dermorphin is about 30-40 times more potent than morphine but less likely to produce drug tolerance and addiction. The amino acid sequence of demorphin is H-Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH2
Dermorphin is not found in humans or other mammals and similar D-amino acid peptides have only been found in bacteria, amphibians and molluscs. Dermorphin appears to be made in these through an unusual posttranslational modification carried out by an amino acid isomerase. The reason why such an unusual process is needed is because the D-alanine in this peptide is not among the 20 in the genetic code and cannot be encoded in the genes by higher organisms.
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What is Delta Sleep Inducing Peptide?

Delta Sleep Inducing Peptide, abbreviated DSIP, is a neuropeptide that when infused into the mesodiencephalic ventricle of recipient rabbits induces spindle and delta EEG activity and reduced motor activities.
Its aminoacid sequence is Тrр-Аlа-Gly-Gly-Asp-Ala-Ser-Gly-Glu. However, it is the only neuropeptide in history whose gene is unknown, raising serious questions regarding the actual existence of this peptide in nature.
Structure
DSIP is an amphiphilic peptide of molecular weight 850 daltons with the amino acid motif:N-Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu-C
Delta Sleep Inducing Peptide has been found in both free and bound forms in the hypothalamus, limbic system and pituitary as well as various peripheral organs, tissues and body fluids. In the pituitary it co-localises with many peptide and non-peptide mediators such as corticotropin-like intermediate peptide (CLIP), adrenocorticotrophic hormone (ACTH), melanocyte-stimulating hormone (MSH), thyroid-stimulating hormone (TSH) and melanin concentrating hormone (MCH). It is abundant in the gut secretory cells and in the pancreas where it co-localises with glucagon.
In the brain its action may be mediated by NMDA receptors. In another study Delta sleep-inducing peptide stimulated Acetyltransferase activity through α1 receptors in rats. It is unknown where Delta Sleep Inducing Peptide is synthesized.
In vitro it has been found to have a low molecular stability with a half life of only 15 minutes due to the action of a specific aminopeptidase-like enzyme. Delta Sleep Inducing Peptide has been suggested that in the body it complexes with carrier proteins to prevent degradation, or exists as a component of a large precursor molecule, but as yet no structure or gene has been found for this precursor.
Evidence supports the current belief that it is regulated by glucocorticoids.
Gimble et al. suggest that DSIP interacts with components of the MAPK cascade and is homologous to glucocorticoid-induced leucine zipper (GILZ). GILZ can be induced by Dexamethasone. It prevents Raf-1 activation, which inhibits phosphorylation and activation of ERK.
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