Leuprorelin (INN) or leuprolide acetate (USAN) is a GnRH analog. Proper Sequence: Pyr-His-Trp-Ser-Tyr-D-Leu-Leu-Arg-Pro-NHEt (Pyr = L-Pyroglutamyl)
Leuprolide acetate is a synthetic nonapeptide analog of naturally occurring gonadotropin releasing hormone (GnRH or LH-RH). The analog possesses greater potency than the natural hormone. The chemical name is 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl-Nethyl-L-prolinamide acetate (salt) with the coming after structural formula.
MT costs available in a 2.8 mL multiple-dose vial comprising leuprolide acetate (pentad mg/mL), sodium chloride, USP (6.3 mg/mL) for tonicity adjustment, benzyl alcohol, NF as a preservative (9 mg/mL), and water for injection, USP. The pH may have been adjusted with sodium hydroxide, NF and/or acetic acid, NF. The injections will usually be given by your GP or practice nurse at the surgery. If you are not able to visit the surgery, a district harbor can consecrate you the injection at home. Some people can be taught to give themselves the injection, if they wish to do so.
Before using leuprolide, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may control in abeyance ingredients (so much as the preservative benzyl alcohol), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
More information: Leuprorelin Acetate
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