Monday, November 28, 2011

How to Get Polypeptide

Polypeptide is a peptide, such as a small protein, containing many molecules of amino acids, typically between 10 and 100. It consists of 2 or more amino acids. The PolyPeptide Group is a world leader in the industrial/commercial-scale manufacture of proprietary and generic GMP and non-GMP peptides.
The amino acids are linked covalently by peptide bonds. The graphic on the right shows how three amino acids are linked by peptide bonds into a tripeptide.One end of every polypeptide, called the amino terminal or N-terminal, has a free amino group. The other end, with its free carboxyl group, is called the carboxyl terminal or C-terminal.
The sequence of amino acids in a polypeptide is dictated by the codons in the messenger RNA (mRNA) molecules from which the polypeptide was translated. The sequence of codons in the mRNA was, in turn, dictated by the sequence of codons in the DNA from which the mRNA was transcribed. The schematic below shows the N-terminal at the upper left and the C-terminal at the lower right.
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